Supported by

Bioinformatics

What we do

Our Bioinformatics program uses cutting edge technologies including next-generation sequencing, comparative genomics and structural bioinformatics techniques to study plant and microbial genomes and host-pathogen interactions.

Why we do it

We’re studying how pathogens adapt, leading to predictions of where the disease-causing genes may be located on a genome. As a result, the time it takes to identify the causes of diseases can be dramatically reduced, with potential to fast track important genetic information through to plant breeders and farmers.

A recent outcome

Distinctive evolutionary patterns of fungal genomes have been observed by using bioinformatics technology, which has helped to predict host specific and/or laterally transferred pathogenicity genes, potentially pointing to mutation hotspots.

  • The Bioinformatics team

  • A circos plot of a whole fungal genome.

  • CCDM's Rob Syme discusses his work in pulse pathogens

  • We're searching big data for disease resistance in crops. Click the picture to read more.

Interested in doing a PhD? Here are a few to choose from:

  • Geographic monitoring for agricultural crop disease
  • Pathogenicity effector discovery via large-scale protein sequence and structure similarity searches
  • Hunting for viral sequences and viral remnants in fungal genomes and RNA-seq next-generation sequencing data
  • Comparative genomics of fungal pathogens of an emerging crop, narrow-leaf lupin
  • Establishing bioinformatic database resources for pathogenicity effectors that will help improve crop resistance to fungal and bacterial pathogens

For project outlines visit our 'study with us' page. Contact James Hane for more information.